Paul Calabresi K12 Career Development Award Program in Clinical Oncology
The Paul Calabresi K12 Career Development Award Program in Clinical Oncology is designed to train a new generation of highly skilled investigators with specialized expertise who will be well prepared to lead cancer research. The K12 Clinical Oncology program supports the development of postdoctoral scholars and junior faculty through patient oriented cancer research training, curricula, and mentored projects.
Applications for the K12 Program are accepted annually from June 1 – September 15.
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75% of a K12 Scholar’s salary (up to $100,000 per year) is provided by the program. Surgeons may request a lower level of effort, but not less than 50%.
Protected Research Time
A minimum of 75% protected time must be guaranteed by each KL2 scholar’s department. Surgeons may only be allowed 50% protected research time.
Up to $25,000 per year in research funds and support for travel are provided to each scholar annually.
Tuition is provided for graduate-level coursework, including but not limited to: the Certificate in Clinical Investigation, the Master of Science in Clinical Investigation (MSCI), or the Master of Population Health Sciences (MPHS)
Clinical Research Training Center (CRTC)
K12 scholars have access to the Clinical Research Training Center. The CRTC provides computer labs, break-out rooms, classroom, poster printing, and administrative office suites
Continuation in the K12 Career Development Awards Program is determined yearly based upon satisfactory research progress, professional effort, academic grades, and attendance and participation in CRTC events.
K12 Scholars are expected to devote 75% of their full-time effort to the training and clinical research activities.
Scholars’ remaining effort may be devoted to other clinical or academic pursuits consistent with the award. NIH policy requires that the remainder of a scholar’s salary (the portion NOT paid by the K12 program) must come from non-federal sources.
Developing a successful clinical and translational research career requires strong relationships with mentors and a research team. Each scholar must have program-approved primary and secondary mentors. The primary mentor will be the scholar’s main source of research supervision and career development. Scholars are expected to meet with their mentors monthly. K12 mentors are expected to be available for consultation and support concerning the scholar’s current projects and future progress. K12 mentors are also expected to provide formal feedback to the scholar at least annually.
Individual Development Plans
K12 scholars must establish a Individual Development Plan in consultation with their mentors and advisory committee. This plan must be submitted annually.
All Individual Development Plans should include:
- Individual development goals for the next 1-5 years
- Career objectives for each goal – For each objective, the scholar should indicate what individual products (degrees, publications, presentations, grants, etc.) are expected
- Research activities and projects that will assist the scholar in meeting the objectives
- An overview of the courses, workshops and other educational/training activities that the Scholar plans to pursue
- A timeline should also be constructed to display the individual objectives, educational activities, research activities, and products
Scholars are required to provide to the Program current IRB approvals for their research project(s).
Responsible Conduct of Research (RCR)
Scholars are required to complete the course Ethical and Legal Issues in Clinical Research (M17-510) during their time in the program or a minimum of eight contact hours consisting of face-to-face or small group discussions in the responsible conduct of research led by expert faculty as part of their training in the Responsible Conduct of Research. Scholars must also comply with Responsible Conduct of Research (RCR) Guidelines for the duration of the program.
All presentations and publications related to research funded by the K12 must cite the appropriate grant award. View Citation Guidelines for more details.
Scholars are to keep the Program informed of their individual progress including published manuscripts, abstracts, submitted grant applications and awards in a timely manner. Additionally, at least once each year, all Scholars are required to provide a progress report detailing their research-in-progress.
Scholars are required to submit a budget to the CRTC Financial Coordinator prior to the start of their program appointment and each subsequent year of the program. This budget must outline projected expenses to be covered by research funds. Budget revisions and expense reports are required as incurred. All scholars are expected to follow the financial policies of the Program. Failure to follow Program policies may result in denial of reimbursement or purchase requests.
Scholars are expected to complete required program evaluations twice per year. These evaluations are administered online and are mandatory for all scholars.
Level of Education
K12 scholars must possess a doctoral-level degree. This includes, but is not limited to: MD, PhD, PharmD, DVM, DrPH, DO, DDS, PsyD, DOT, DPT, DC, DSN, or DNSc as well as biostatisticians, epidemiologists, behavioral scientists, and nurses with doctoral degrees.
Eligible applicants must be citizens or non-citizen nationals of the United States, or have been lawfully admitted to the United States for permanent residence and have in their possession an Alien Registration Receipt Card (I-151 or I-551) or other legal verification of admission for permanent residence. Non-citizen nationals are persons born in lands that are not States but are under U.S. sovereignty, jurisdiction, or administration (e.g., American Samoa). Individuals on visas are not eligible.
Individuals applying to the K12 Program should be at an early stage of their career. The K12 Program expects applicants to be postdoctoral level trainees or early junior faculty level trainees who plan to conduct, or are conducting, clinical oncology research.
The K12 award is not intended for individuals making mid-career changes into clinical oncology research.
At the time of application, you do not have to have a faculty appointment. However, if selected as a K12 scholar, you will need a faculty appointment by the time you begin the program.
All K12 scholars must be able to devote 75% professional effort to the program for a minimum of two years (surgeons may request a lower level of effort, but not less than 50%).
K12 scholars must have the support of two mentors. These mentors must be approved by the Program and must come from two different disciplines. In addition one should be a clinician conducting patient-oriented research and the other a basic science cancer researcher.
Principal Investigator Status
The applicant may be or have been a principal investigator (PI) of NIH R03 and R21 grants or non-PHS equivalents at the time of application. Applicants cannot have been a PI on an NIH research grant (such as R01, R29, or P01) or a non-NIH equivalent to these grants. The applicant may have had support from a National Research Service Award (F or T) or an NIH small grant (R03).
Federal Salary Support
Applicants may not obtain salary support from other federal grants until the final two years of mentored K support (NOT-OD-08-065). Applicants may not obtain support if previously supported on a K award beyond 5 years.
If a potential scholar is already studying under an existing K12, he/she is still eligible for the K12 program. However, the cumulative length of time under NIH-sponsored K programs should be no more than 5 years. The minimum amount of time any one Scholar may spend in this Trans-NIH K12 program is two years, K12 applicants may not have had more than three years of support under the previous K12 program. Furthermore, the K12 applicant would need to justify the need for additional mentored research training or training in a team context as it is not advised for one’s career development to transfer from another Institutional K-Award to the K12 Program.
The applicant may not have another K award pending.
- Application Form
- Current Biosketch or Curriculum Vitae
- Other Support
- Individual Development Plan
- Research Plan
- Primary Mentor Biosketch
- Primary Mentor Other Support
- Primary Mentor Training Table
- Primary Mentor Letter of Support
- Secondary Mentor Biosketch
- Secondary Mentor Other Support
- Secondary Mentor Training Table
- Secondary Mentor Letter of Support
- Department Chair Recommendation Letter
- Second Recommendation Letter
- Third Recommendation Letter
Please read the following prior to filling out an application:
- Only complete applications will be reviewed. Applications will not be considered as complete until all supporting documents have been submitted. All application materials must be submitted online. Supporting documents may be updated and re-submitted online prior to the application deadline. Please note that the selection committee will only receive the last version uploaded for each document. Failure to upload all required documents and letters (complete and in the proper format) will result in the application not being reviewed. Missing EVEN ONE (1) item by the deadline will result in the application being rejected. It is the responsibility of the applicant to monitor the status of ALL required documents.
- If you have previously applied to the K12 program, you must complete a new application for the current cycle.
- Applicants must complete and SUBMIT the online application form before supporting documents may be uploaded. This includes the Mentor Letter of Support and the Recommendation Letter.
Current Biosketch and Other Support
Each applicant is required to submit a current NIH Biosketch and Other Support documents.
NIH Biosketch Template »
NIH Other Support Template »
Individual Development Plan
Applicant must submit a 3-5 page individual development plan (no more than 5 pages; references are not included in page count) that includes, but is not limited to, the following:
- Career goals
- Past research experience and past graduate coursework that is relevant
- Who your mentors are and why you have selected them
- Coursework you are planning to take and why
- The number of years you anticipate being on the K12 award
- Your plans for the next 2-3 years if you do not receive the award
- How the award will change or affect your career plans
The required Research Plan should follow the standard NIH format (PHS 398).
Please note the new NIH requirements for this section around Rigor and Reproducibility: http://grants.nih.gov/reproducibility/faqs.htm#4834
The Research Plan includes:
|Section of Research Plan
|Introduction (Resubmission Only; NIH PHS 398 form is NOT required)
|Specific Aims & Research Strategy (Significance, Innovation, and Approach)
|Protection of Human Subjects, Inclusion of Women and Minorities, Inclusion of Children, Vertebrate Animals
|Targeted/Planned Enrollment Table
|Bibliography and References Cited/Progress Report Publication List (include PMCID # if applicable) and Consortium/Contractual Arrangements
||No Page Limit
Mentoring is a critical part of the K12 Career Development Awards, and who your mentors are is very important. The K12 application requires two mentors. Applicants must identify one mentor as primary and one as secondary. Applicants must establish a relationship with the proposed mentor prior to submission of the K12 Career Development application. Please do not select a mentor without prior approval of the mentor.
The review of your K12 application will include a critique of your selected mentors. Reviewers will examine whether they are appropriate and suitable for your research project and career development. Please be sure that your mentors are the best suited for you and your research, and not simply meeting the minimum qualifications required of a K12 mentor.
Program faculty should have strong records as researchers, including recent publications and successful competition for research support in the area of the proposed research training program. Program faculty should also have a record of research training, including successful, former trainees who have established productive careers relevant to the NIH mission. Researchers from diverse backgrounds, including racial and ethnic minorities, persons with disabilities, and women are encouraged to participate as mentors.
Mentors must be committed to continue their involvement throughout the total period of the award. Mentors are expected to have independent R01 and/or R01-like cancer related research support. For the K12 program, R01 and/or R01-like awards are grants or contracts of at least 3 years duration and $150,000/year in direct costs, including those supporting clinical trials.
Applicants must have both a primary and secondary mentor and one must be a clinician conducting patient-oriented research and the other a basic science cancer researcher
- If the mentor(s) of an applicant has selected do not already appear in the online application, please be sure that they are qualified to be a mentor (see FAQ) and are willing to dedicate the time to you and this program.
- Please email the K12 program if you would like to have a mentor approved for the K12 application.For approval, please submit the proposed mentor’s NIH Biosketch, Other Support Form, and Trainee Table documents. The application form and subsequent supporting documents cannot be submitted until a mentor has been approved and selected in the online form. All mentors will ultimately need to be approved by the Program and the NIH, therefore, new mentor approvals must be completed well in advance of the deadline.
Each proposed mentor must provide a letter of support, an updated NIH Biosketch, Other Support, and Trainee Tables by the application deadline. Upon submission of the online application form, an email will be automatically generated to each mentor with guidelines and instructions on how to upload the required letter. It is the responsibility of the applicant to verify that the identified mentors have received the emails. Applicants may view a confirmation of the documents that have been uploaded via the online application site.
Mentor letters must:
- Be uploaded by the mentor, not the applicant
- Include the mentor’s signature
- Be submitted on the mentor’s letterhead
Department Chair Recommendation Letter
Each applicant’s Department Chair or Division Chief is required to submit a letter of support describing the applicant’s potential and guaranteeing the protected time (75%) required for participation in the K12 Career Development Program. This letter of support must be uploaded by the application deadline (September 15). Upon submission of the online application form, an email will be automatically generated to the identified Department Chair or Division Chief with guidelines and instructions regarding how to upload the required letter. It is the responsibility of the applicant to verify that the identified reference has received the email. The online application site provides applicants with a checklist on which they may view confirmation of the documents that have been uploaded to their application.
Letters of Recommendation from the Department Chair or Division Chief must:
- Be uploaded by the Department Chair or the Division Chief, not the applicant
- Include the Department Chair or the Division Chief’s signature
- Be submitted on letterhead
The last document uploaded will be the document reviewed. It is important for the Department Chair to understand that their letters must include a signature and be on official letterhead. The link sent to each Department Chair is unique for each applicant, and one link cannot be used to upload documents for multiple applicants.
All Recommendation Letters
Each applicant is required to have 2 letters of recommendation submitted by references in addition to the Department or Division Head. These letters should describe the applicant’s potential to succeed as an independent researcher. All letters of recommendation must be uploaded by the application deadline. Upon submission of the online application form, an email will be automatically generated to the identified references with guidelines and instructions regarding how to upload the required letter. It is the responsibility of the applicant to verify that the identified reference has received the email. The online application site provides applicants with a checklist on which they may view confirmation of the documents that have been uploaded to their application.
Letters of Recommendation must:
- Be uploaded by reference, not the applicant
- Include the reference’s signature
- Be submitted on an official letterhead
The last document uploaded will be the document reviewed. It is important for references to understand that their letters must include a signature and be on official letterhead. The link sent to each Reference is unique for each applicant, and one link cannot be used to upload documents for multiple applicants.
Required Format for Supporting Documents
- Black font of either Arial, Helvetica, Palatino Linotype or Georgia
- Font size of 11 points or larger (a symbol font may be used to insert Greek letters or special characters; the font size requirement still applies.)
- Type density, including characters and spaces, must be no more than 15 characters per inch
- Single spaced paragraph type
- Margins should be at least one-half inch margins (top, bottom, left, and right) for all pages, including continuation pages
- PDF versions are required
- Appendices are not allowed
Timeline for Applications
- September 15, 5:00 pm (CST) = Due date for submission of complete application materials
- September – December = Internal review of applicants
- December = New K12 Scholars Announced
- February = Mandatory Scholar Orientation
- April 1 = Scholar start date